Feb 12, 2024 | Anaerobe labeling, FAST and splitFAST
FAST in Clostridioides difficile! Already well described in various solventogenic and acetogenic Clostridia strains, FAST is now disclosed for the first time ever in pathogenic C. difficile. A nice work by the team of Prof. Isabelle Martin-Verstraete of Institut...
Feb 5, 2024 | FAST and splitFAST
splitFAST2 is the next-gen complementation system just published in ACS Chem. Biol. 2024 by Prof. Gautier’s team. Remember! In 2019, they introduced splitFAST, a breakthrough complementation reporter for protein−protein interaction (PPIs) based on the...
Jan 22, 2024 | Anaerobe labeling, FAST and splitFAST
Eubacterium strain engineering with FAST is a continued and fruitful focus of Dr. Maximilian Flaiz of Wageningen University and Dr. Franck Bengelsdorf of Ulm University. Indeed, Flaiz et al. have just published “Refining and illuminating acetogenic Eubacterium...
Jan 1, 2024 | FAST and splitFAST, Mammals
A team led by Paola Pizzo and Riccardo Filadi of the University of Padova has just enabled endoplasmic reticulum-mitochondria junction studies with splitFAST of The Twinkle Factory. The interest in such membrane contact sites (MCSs) between membranous organelles has...
Dec 18, 2023 | FAST and splitFAST
Remember the metabolic engineering work in S. cerevisiae based on auxin-mediated protein degradation of the lab of Claudia Vickers from the University of Queensland, Brisbane? They once disclosed in Nat. Commun. 2021 very elegant strategies for metabolic engineering...
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