Stain different, tag FAST
The Twinkle Factory is rooted in the wish of Arnaud Gautier, Ludovic Jullien and Franck Perez, three top-notch scientists of ENS-PSL, Sorbonne University, and Institut Curie to help life science researchers accelerate their work. The Twinkle Factory thus distributes reagents for their breakthrough protein fluorescent reporters and molecular glues, FAST and splitFAST (What is it, FAST and splitFAST?), and CATCHFIRE (What is it, CATCHFIRE?).
It all started in 2019 with a three-item-long pricelist for FAST and splitFAST. Along with cofounders’ research, non-permeant fluorogens, a far-red fluorogen, a fluorescence quencher, have added to the list. As a result, sales rapidly expanded worldwide. So far, 300 research teams at universities, life sciences startups, big pharmas, CROs, have implemented FAST and splitFAST in their research. Their key words are metabolic engineering, microbiota, protein-protein interactions, synthetic biology, cell-based assays, sensors… Furthermore, they unveiled the potential of FAST in hypoxic conditions, equipping a vast array of microorganisms.
And in 2023, we have added a whole range of fluorogenic molecular glues for CATCHFIRE.
This is just the beginning! Actinometers, and many other twinkling reagents are indeed joining the pack. Stay tuned!
Our latest post
Secretory system of Clostridium perfringens with FAST
disclosed by Prof. S. Melville et al. in bioRxiv
Our earlier posts
Endoplasmic reticulum-mitochondria junction studies with splitFAST
by Prof. Pizzo of Padova University
Metabolic engineering in S. cerevisiae with FAST – Cont’d
disclosed by the University of Queensland in ACS Synth. Biol.
Lipid droplets equipped with splitFAST
by St. Jude Children’s Hospital and HHMI’s Janelia campus
Fluorogenic molecular glues for CATCHFIRE now available
Request your two-for-the-price-of-one bonus!
FAST for multicolor imaging of Pseudomonas aeruginosa
phiLOV2.1 and FAST found to be the best match
FAST biosensors: glutamate, K+, ATP, and more to come
just published in ACS Sensors by Prof. A. Gautier’s team
Click-FAST: FAST and click chemistry for à-la-carte fluorescent reporting
just disclosed by researchers of OHSU School of Dentistry
CATCHFIRE, a brandnew self-reporting protein dimerizer
just published in Nat. Methods by A. Gautier and F. Perez
FAST in anaerobic thermophiles for the first time ever
Towards C1-based biofuels and chemicals! By R. Hocq of TU Wien
FAST nanoprobes for anaerobic tracking of gut microbiota vesicles
disclosed by Shanghai Jiao Tong University in ACS Nano
FAST and splitFAST, greenFAST & redFAST, pFAST in a nutshell
A review of this exciting journey in Account Chemistry Research by inventor Prof. Arnaud Gautier
FAST and splitFAST to the fore at CLOSTRIDIUM XVI
three talks and one poster reviewing FAST of The Twinkle Factory in acetogenic and solventogenic Clostridia
Thanks to the continued support of PSL Université and Région Ile-de-France.